Player_Interceptions
| NameFL | TAbb | PosN | Int | IntY | IntAvg | IntL | IntTDs |
| Shawn Springs | SCS | Left CB | 8 | 102 | 12.8 | 25 | 0 |
| Brian Russell | BUF | Free Safety | 8 | 86 | 10.8 | 41 | 1 |
| Marcus Trufant | OAK | Left CB | 7 | 129 | 18.4 | 86 | 1 |
| LaRon Landry | RED | Strong Safety | 7 | 59 | 8.4 | 25 | 0 |
| Chris Harris | LAA | Strong Safety | 6 | 76 | 12.7 | 25 | 0 |
| Brian Dawkins | CAL | Free Safety | 6 | 74 | 12.3 | 25 | 0 |
| Sean Considine | SEA | Strong Safety | 6 | 64 | 10.7 | 48 | 1 |
| Terence Newman | SDC | Left CB | 6 | 61 | 10.2 | 20 | 0 |
| Rashean Mathis | SF4 | Left CB | 6 | 45 | 7.5 | 25 | 0 |
| Leon Hall | RED | Left CB | 5 | 107 | 21.4 | 58 | 1 |
| Lawyer Milloy | DAL | Strong Safety | 5 | 76 | 15.2 | 22 | 0 |
| Adrian Wilson | RED | Strong Safety | 5 | 68 | 13.6 | 25 | 0 |
| Fakhir Brown | NOV | Right CB | 5 | 66 | 13.2 | 25 | 0 |
| Darrelle Revis | PEO | Left CB | 5 | 59 | 11.8 | 20 | 0 |
| Chris McAlister | LAA | Left CB | 5 | 52 | 10.4 | 22 | 0 |
| Antonio Cromartie | PEO | Right CB | 5 | 48 | 9.6 | 22 | 0 |
| Charles Tillman | LAA | Left CB | 5 | 22 | 4.4 | 12 | 0 |
| Adalius Thomas | OAK | Right I LB | 4 | 96 | 24.0 | 71 | 1 |
| Ty Law | CAL | Left CB | 4 | 76 | 19.0 | 22 | 0 |
| Anthony Henry | SEA | Right CB | 4 | 76 | 19.0 | 64 | 1 |
| Nnamdi Asomugha | SDC | Left CB | 4 | 54 | 13.5 | 22 | 0 |
| Sean Taylor | CHI | Free Safety | 4 | 47 | 11.8 | 22 | 0 |
| Josh Bullocks | NOV | Free Safety | 4 | 32 | 8.0 | 20 | 0 |
| O.J. Atogwe | PIT | Free Safety | 4 | 24 | 6.0 | 12 | 0 |
| Nate Clements | SF4 | Left CB | 4 | 24 | 6.0 | 20 | 0 |
| Brandon Meriweather | SF4 | 1st Defensive Back | 4 | 17 | 4.3 | 13 | 0 |
| Ken Hamlin | OAK | Free Safety | 3 | 74 | 24.7 | 58 | 1 |
| Ronde Barber | PHI | Left CB | 3 | 55 | 18.3 | 20 | 0 |
| Kerry Rhodes | CAL | Strong Safety | 3 | 49 | 16.3 | 25 | 0 |
| Ike Taylor | BUF | Left CB | 3 | 49 | 16.3 | 25 | 0 |
| Ernie Sims | NOV | Right LB | 3 | 42 | 14.0 | 20 | 0 |
| Tanard Jackson | PHI | Free Safety | 3 | 34 | 11.3 | 12 | 0 |
| Terrence McGee | OAK | Right CB | 3 | 34 | 11.3 | 22 | 0 |
| Johnathan Joseph | SCS | Right CB | 3 | 34 | 11.3 | 12 | 0 |
| Nick Harper | PIT | Left CB | 3 | 30 | 10.0 | 20 | 0 |
| Bradie James | BUF | Left I LB | 3 | 25 | 8.3 | 13 | 0 |
| Chris Hope | PHI | Strong Safety | 3 | 24 | 8.0 | 10 | 0 |
| Antoine Bethea | SCS | Free Safety | 3 | 12 | 4.0 | 12 | 0 |
| Aaron Ross | OAK | Left CB | 3 | 10 | 3.3 | 10 | 0 |
| Sammy Knight | DAL | Strong Safety | 3 | 10 | 3.3 | 10 | 0 |
| Lance Briggs | SF4 | Right LB | 2 | 105 | 52.5 | 92 | 2 |
| Deon Grant | NOV | Strong Safety | 2 | 102 | 51.0 | 82 | 1 |
| Dre' Bly | PHI | Right CB | 2 | 86 | 43.0 | 76 | 1 |
| Kawika Mitchell | SF4 | Right LB | 2 | 75 | 37.5 | 53 | 1 |
| Angelo Crowell | CAL | Left LB | 2 | 38 | 19.0 | 25 | 0 |
| Sean Jones | SF4 | Strong Safety | 2 | 37 | 18.5 | 25 | 0 |
| Quintin Mikell | RED | 1st Defensive Back | 2 | 35 | 17.5 | 22 | 0 |
| Bob Sanders | SEA | Strong Safety | 2 | 34 | 17.0 | 22 | 0 |
| Ed Reed | OAK | Free Safety | 2 | 30 | 15.0 | 20 | 0 |
| Troy Polamalu | SCS | Strong Safety | 2 | 28 | 14.0 | 15 | 0 |
| Gibril Wilson | PIT | Free Safety | 2 | 27 | 13.5 | 27 | 1 |
| Clinton Hart | PHO | Strong Safety | 2 | 26 | 13.0 | 22 | 0 |
| Darren Sharper | LAA | Strong Safety | 2 | 26 | 13.0 | 13 | 0 |
| Jermaine Phillips | BUF | Strong Safety | 2 | 22 | 11.0 | 22 | 0 |
| Dunta Robinson | PHO | Left CB | 2 | 20 | 10.0 | 20 | 0 |
| Charles Woodson | SEA | Left CB | 2 | 8 | 4.0 | 4 | 0 |
| Ellis Hobbs | BUF | Right CB | 2 | 4 | 2.0 | 4 | 0 |
| Champ Bailey | PIT | Left CB | 2 | 0 | 0.0 | 0 | 0 |
| Al Harris | DAL | Right CB | 2 | 0 | 0.0 | 0 | 0 |
| Sheldon Brown | CAL | Right CB | 2 | 0 | 0.0 | 0 | 0 |
| David Thornton | CAL | Left LB | 1 | 99 | 99.0 | 99 | 1 |
| Robert Geathers | OAK | Left End | 1 | 59 | 59.0 | 59 | 1 |
| Takeo Spikes | DAL | Right LB | 1 | 39 | 39.0 | 39 | 1 |
| Jonathan Babineaux | RED | Right Tackle | 1 | 32 | 32.0 | 32 | 1 |
| Brady Poppinga | SEA | Left LB | 1 | 26 | 26.0 | 26 | 1 |
| Michael Huff | PEO | Strong Safety | 1 | 25 | 25.0 | 25 | 0 |
| Will Allen | NOV | Left CB | 1 | 25 | 25.0 | 25 | 0 |
| Phillip Buchanon | CAL | Right CB | 1 | 22 | 22.0 | 22 | 0 |
| Roy Williams | SF4 | Strong Safety | 1 | 22 | 22.0 | 22 | 0 |
| James Harrison | NOV | Right O LB | 1 | 22 | 22.0 | 22 | 0 |
| Jared Allen | SF4 | Right End | 1 | 20 | 20.0 | 20 | 0 |
| Kelvin Hayden | PEO | Left CB | 1 | 20 | 20.0 | 20 | 0 |
| Marcus Washington | SCS | Left LB | 1 | 20 | 20.0 | 20 | 0 |
| Michael Boley | PIT | Left LB | 1 | 20 | 20.0 | 20 | 0 |
| James Sanders | PEO | Free Safety | 1 | 20 | 20.0 | 20 | 0 |
| Derrick Brooks | PHI | Right LB | 1 | 15 | 15.0 | 15 | 0 |
| Victor Hobson | OAK | Right O LB | 1 | 15 | 15.0 | 15 | 0 |
| DeAngelo Hall | RED | Left CB | 1 | 15 | 15.0 | 15 | 0 |
| Gary Brackett | SF4 | Middle LB | 1 | 15 | 15.0 | 15 | 0 |
| Keith Bulluck | PHI | Right LB | 1 | 15 | 15.0 | 15 | 0 |
| Lito Sheppard | DAL | Left CB | 1 | 13 | 13.0 | 13 | 0 |
| Darnell Dockett | LAA | Left Tackle | 1 | 13 | 13.0 | 13 | 0 |
| Walt Harris | CHI | Right CB | 1 | 13 | 13.0 | 13 | 0 |
| Calvin Pace | PHO | Left LB | 1 | 13 | 13.0 | 13 | 0 |
| Aaron Schobel | CHI | Right End | 1 | 13 | 13.0 | 13 | 0 |
| Brodney Pool | PHO | Free Safety | 1 | 12 | 12.0 | 12 | 0 |
| Pat Williams | DAL | Left Tackle | 1 | 12 | 12.0 | 12 | 0 |
| Donte Whitner | SDC | Strong Safety | 1 | 12 | 12.0 | 12 | 0 |
| Trumaine McBride | PHI | Right CB | 1 | 12 | 12.0 | 12 | 0 |
| Brian Williams | LAA | Right CB | 1 | 10 | 10.0 | 10 | 0 |
| Asante Samuel | CHI | Left CB | 1 | 10 | 10.0 | 10 | 0 |
| Daryl Smith | CHI | Right LB | 1 | 4 | 4.0 | 4 | 0 |
| Antoine Winfield | PHO | Left CB | 1 | 4 | 4.0 | 4 | 0 |
| Richard Marshall | SDC | CB | 1 | 4 | 4.0 | 4 | 0 |
| Derrick Johnson | PEO | Left LB | 1 | 4 | 4.0 | 4 | 0 |
| DeMeco Ryans | SEA | Middle LB | 1 | 4 | 4.0 | 4 | 0 |
| Patrick Surtain | SEA | Right CB | 1 | 4 | 4.0 | 4 | 0 |
| Leroy Hill | RED | Left LB | 1 | 4 | 4.0 | 4 | 0 |
| Bernard Pollard | SEA | Strong Safety | 1 | 0 | 0.0 | 0 | 0 |
| Marlin Jackson | PHO | Right CB | 1 | 0 | 0.0 | 0 | 0 |
| Shaun Phillips | SDC | Right O LB | 1 | 0 | 0.0 | 0 | 0 |
| Atari Bigby | PEO | Strong Safety | 1 | 0 | 0.0 | 0 | 0 |
| Sum | --- | --- | 260 | 3532 | 13.6 | 2312 | 18 |
| Avg | --- | --- | 3 | 35 | 13.6 | 23 | 0 |