Player_Sacks
| NameFL | TAbb | PosN | Sack | SackYds |
| Greg Ellis | SF4 | Left O LB | 18 | 123 |
| Jason Taylor | STL | Right End | 15 | 114 |
| Aaron Schobel | GRR | Right End | 14 | 101 |
| Osi Umenyiora | GRR | Right End | 13 | 105 |
| John Abraham | SF4 | Right End | 10 | 75 |
| Gaines Adams | PIT | Right End | 10 | 73 |
| Elvis Dumervil | HAM | Right End | 9 | 74 |
| Jovan Haye | SF4 | Right Tackle | 9 | 56 |
| Shaun Rogers | GRR | Right Tackle | 9 | 55 |
| Jared Allen | BAC | Right End | 8 | 61 |
| Trent Cole | SDC | Right End | 8 | 56 |
| Adewale Ogunleye | CHI | Left End | 8 | 55 |
| Bryant Young | SDC | Left End | 8 | 51 |
| Hollis Thomas | PHS | Left Tackle | 7 | 51 |
| Julian Peterson | NYG | Right LB | 7 | 50 |
| Andre Carter | ARI | Right End | 7 | 49 |
| Robert Mathis | PIT | Left End | 7 | 46 |
| La'Roi Glover | SJS | Left Tackle | 7 | 46 |
| Aaron Kampman | NOV | Left End | 7 | 43 |
| Mario Williams | ARI | Right End | 6 | 44 |
| Mike Patterson | DAL | Left Tackle | 6 | 40 |
| Willie McGinest | PHS | Left O LB | 6 | 39 |
| Shawne Merriman | MON | Left O LB | 6 | 37 |
| Greg White | SHR | Def End | 6 | 36 |
| Donnie Edwards | BAC | Right LB | 5 | 46 |
| Paul Spicer | PHS | Right End | 5 | 42 |
| Brent Hawkins | NYG | Def End | 5 | 42 |
| Kawika Mitchell | PIT | Right LB | 5 | 37 |
| Justin Tuck | BAC | Def End | 5 | 33 |
| Darnell Dockett | TBB | Left Tackle | 5 | 31 |
| Dewayne Robertson | DAD | Nose Tackle | 5 | 29 |
| Brian Urlacher | ARI | Middle LB | 5 | 28 |
| Edgar Jones | SDC | O LB | 5 | 28 |
| Jamar Williams | BER | LB | 5 | 13 |
| Ray Lewis | GRR | Left I LB | 5 | 13 |
| Brodrick Bunkley | NYJ | Right Tackle | 5 | 10 |
| Rob Meier | OAK | Def Tackle | 4 | 36 |
| Clifton Ryan | ARI | Def Tackle | 4 | 33 |
| John Henderson | PIT | Right Tackle | 4 | 32 |
| Ray Edwards | GBP | Right End | 4 | 30 |
| Patrick Kerney | MON | Left End | 4 | 30 |
| Joey Porter | CHI | Left LB | 4 | 29 |
| Kyle Vanden Bosch | DAD | Right End | 4 | 28 |
| Pisa Tinoisamoa | ARI | Right LB | 4 | 28 |
| Derrick Burgess | NYJ | Right End | 4 | 26 |
| Brian Dawkins | GRR | Free Safety | 4 | 26 |
| Ryan Fowler | SF4 | Middle LB | 4 | 23 |
| Kabeer Gbaja-Biamila | NOS | Def End | 4 | 22 |
| Amobi Okoye | BAC | Left Tackle | 4 | 21 |
| Greg Spires | BAL | Def End | 4 | 21 |
| Fred Robbins | BAL | Right Tackle | 4 | 14 |
| Keith Traylor | PHS | Left Tackle | 4 | 9 |
| Marcus R. Spears | HAM | Left End | 3 | 30 |
| Charles Grant | MON | Left End | 3 | 26 |
| Calvin Pace | DAL | Left LB | 3 | 25 |
| Justin Smith | OAK | Right End | 3 | 24 |
| Jeff Charleston | SCS | Def End | 3 | 24 |
| Travis LaBoy | PHI | Def End | 3 | 23 |
| Cornelius Griffin | DET | Left Tackle | 3 | 22 |
| Ian Gold | SF4 | Right LB | 3 | 21 |
| Will Smith | NJG | Right End | 3 | 21 |
| Jevon Kearse | DAD | Def End | 3 | 21 |
| James Harrison | STL | Right O LB | 3 | 20 |
| Vonnie Holliday | DAD | Right Tackle | 3 | 20 |
| Jarrad Page | NYJ | Free Safety | 3 | 20 |
| Larry Foote | PHS | Right I LB | 3 | 19 |
| Shaun Ellis | BER | Left End | 3 | 19 |
| Marcus Stroud | PHI | Left Tackle | 3 | 18 |
| Kenechi Udeze | WAS | Left End | 3 | 16 |
| Aaron Ross | GRR | Left CB | 3 | 16 |
| Eric Barton | DAD | Left I LB | 3 | 15 |
| Mike Vrabel | BER | Left O LB | 3 | 14 |
| E.J. Henderson | SDC | Middle LB | 3 | 13 |
| Grady Jackson | CHI | Def Tackle | 3 | 12 |
| Jay Ratliff | NOS | Nose Tackle | 3 | 11 |
| Albert Haynesworth | BER | Right Tackle | 3 | 9 |
| Antonio Pierce | OAK | Middle LB | 3 | 7 |
| Michael Strahan | SF4 | Left End | 2 | 22 |
| Michael Boley | BER | Left LB | 2 | 20 |
| Cato June | SDC | Left LB | 2 | 19 |
| Igor Olshansky | BUF | Left End | 2 | 18 |
| Jared DeVries | CHI | Left End | 2 | 18 |
| Chris Wilson | PHS | Def End | 2 | 17 |
| Robert Geathers | BUF | Left End | 2 | 17 |
| Marques Douglas | DAL | Right End | 2 | 16 |
| Julius Peppers | PHI | Left End | 2 | 16 |
| Rosevelt Colvin | TBB | Right O LB | 2 | 16 |
| Kevin Carter | NOS | Left End | 2 | 15 |
| Josh Mallard | DET | Def End | 2 | 15 |
| Phillip Daniels | NYG | Left End | 2 | 15 |
| Lance Briggs | STL | Right LB | 2 | 15 |
| Rocky Bernard | TBB | Right Tackle | 2 | 14 |
| Terence Newman | ARI | Left CB | 2 | 14 |
| Ernie Sims | HAM | Right LB | 2 | 13 |
| Richard Seymour | SDC | Right End | 2 | 13 |
| Tamba Hali | STL | Left End | 2 | 13 |
| James Farrior | HAM | Left I LB | 2 | 13 |
| Ronald Fields | TBB | Def End | 2 | 13 |
| Dewayne White | TBB | Right End | 2 | 13 |
| DeMarcus Ware | WAS | Right O LB | 2 | 11 |
| Haloti Ngata | OAK | Right End | 2 | 11 |
| Brian Robison | SCS | Def End | 2 | 10 |
| Thomas Howard | GRR | Left LB | 2 | 10 |
| Adalius Thomas | CHI | Right I LB | 2 | 10 |
| Brady Poppinga | NOS | Left LB | 2 | 10 |
| Barry Cofield | NOV | Left Tackle | 2 | 8 |
| Kyle Williams | SCS | Right Tackle | 2 | 8 |
| Jonathan Babineaux | PIT | Right Tackle | 2 | 8 |
| Terrence Holt | PHS | Free Safety | 2 | 8 |
| Patrick Willis | MON | Right I LB | 2 | 7 |
| Parys Haralson | BUF | Left O LB | 2 | 6 |
| Will Witherspoon | NJG | Middle LB | 2 | 6 |
| Brandon Mebane | PHI | Left Tackle | 2 | 4 |
| Chris Hovan | OAK | Left Tackle | 2 | 2 |
| Omar Gaither | NOS | Middle LB | 2 | 1 |
| Chris Hoke | NYG | Nose Tackle | 2 | 0 |
| Warren Sapp | WAS | Left Tackle | 2 | 0 |
| Nick Barnett | NYJ | Middle LB | 2 | 0 |
| Jarvis Green | NYJ | Def End | 1 | 12 |
| David Thornton | PHI | Left LB | 1 | 11 |
| Jay Richardson | WAS | Def End | 1 | 11 |
| Bart Scott | PIT | Right I LB | 1 | 11 |
| Dashon Goldson | DAD | 1st Defensive Back | 1 | 11 |
| Brandon T. Moore | BUF | O LB | 1 | 11 |
| Dunta Robinson | NOV | Left CB | 1 | 10 |
| Brodney Pool | NJG | Free Safety | 1 | 10 |
| Daryl Smith | GRR | Right LB | 1 | 10 |
| Mathias Kiwanuka | SCS | Left LB | 1 | 10 |
| Reggie Nelson | SF4 | Free Safety | 1 | 10 |
| Roy Williams | STL | Strong Safety | 1 | 9 |
| Randall Gay | PIT | 1st Defensive Back | 1 | 9 |
| Tank Williams | DAD | 1st Defensive Back | 1 | 9 |
| Darryl Tapp | NOV | Right End | 1 | 9 |
| Kelvin Hayden | GRR | Left CB | 1 | 9 |
| Leroy Hill | DAD | Left LB | 1 | 9 |
| Casey Hampton | GBP | Nose Tackle | 1 | 8 |
| Aaron Smith | SHR | Left End | 1 | 8 |
| Chris Canty | STL | Right End | 1 | 8 |
| Bryan Thomas | NYG | Left O LB | 1 | 8 |
| Gerard Warren | BER | Right Tackle | 1 | 8 |
| Terrell Suggs | BAC | Right O LB | 1 | 7 |
| Ty Warren | DAL | Left End | 1 | 7 |
| Cory Redding | BAL | Left Tackle | 1 | 7 |
| Shawn Springs | STL | Left CB | 1 | 7 |
| Victor Hobson | CHI | Right O LB | 1 | 7 |
| Eric Smith | SCS | 1st Defensive Back | 1 | 7 |
| Chris Gocong | ARI | Left LB | 1 | 7 |
| Chris Kelsay | CHI | Left End | 1 | 7 |
| Anthony Maddox | DET | Def Tackle | 1 | 6 |
| Antwan Peek | SJS | O LB | 1 | 6 |
| Stephen Cooper | NOS | Right I LB | 1 | 5 |
| Pat Williams | GRR | Left Tackle | 1 | 5 |
| Shaun Phillips | SJS | Right O LB | 1 | 4 |
| Vince Wilfork | SF4 | Nose Tackle | 1 | 4 |
| Ike Taylor | SHR | Left CB | 1 | 4 |
| Tommie Harris | NJG | Left Tackle | 1 | 4 |
| Morlon Greenwood | NYJ | Right LB | 1 | 3 |
| Atari Bigby | GRR | Strong Safety | 1 | 3 |
| Darwin Walker | HAM | Right Tackle | 1 | 3 |
| Leon Williams | PHI | I LB | 1 | 3 |
| Greg Peterson | ARI | Def Tackle | 1 | 2 |
| Jon Beason | TBB | Middle LB | 1 | 2 |
| Derek Smith | SJS | Left I LB | 1 | 2 |
| Hamza Abdullah | MON | Strong Safety | 1 | 2 |
| Kirk Morrison | BAL | Middle LB | 1 | 1 |
| Jamal Williams | STL | Nose Tackle | 1 | 0 |
| Barrett Ruud | SHR | Middle LB | 1 | 0 |
| Ryan Pickett | BAC | Left Tackle | 1 | 0 |
| Gary Brackett | BUF | Middle LB | 1 | 0 |
| Aaron Francisco | SDC | 1st Defensive Back | 1 | 0 |
| London Fletcher | NOV | Middle LB | 1 | 0 |
| Keith Brooking | WAS | Middle LB | 1 | 0 |
| Lofa Tatupu | GBP | Middle LB | 1 | 0 |
| Anthony Montgomery | BUF | Right Tackle | 1 | 0 |
| Sum | --- | --- | 548 | 3497 |
| Avg | --- | --- | 3 | 20 |